Home Vermillion

Vermillion's by-appointment veterinary clinic.

A second home for Lewis & Clark Veterinary Clinic, right in the heart of Vermillion. Personal, unhurried visits scheduled around your day — serving Clay County's pet families with the same Fear Free certified team that cares for Yankton.

Address 306 Bower Street
Vermillion, SD 57069 Get directions

Hours By appointment Hours vary — call ahead

Phone (605) 260-5650 Texting available via Otto

Book Request an appointment online Request Appointment

Our Vermillion clinic

Closer than ever, with the care you trust.

Our Vermillion location was created for pet families who'd rather not make the drive to Yankton for routine care. Here, visits are scheduled by appointment so there's never a rushed day — just one-on-one time with your veterinarian, on a schedule that works for you.

We're on Bower Street, just a short walk from the University of South Dakota and downtown Vermillion. Families come to us from Vermillion, Elk Point, Beresford, North Sioux City, and the surrounding Clay County area.

For surgeries, advanced diagnostics, large animal needs, or anything urgent — our full Yankton facility is just a 30-minute drive west, with the same team and the same records.

Lewis & Clark Veterinary Clinic in Vermillion, SD — quiet, neighborhood-feel exterior

A cat relaxing in a cozy cubby in the clinic's feline-friendly space

By appointment

Why Vermillion

A different kind of appointment.

Designed for the way you actually want to visit the vet — closer to home, unhurried, and connected to the same team that cares for you in Yankton.

01 — Time

Unhurried visits.

By-appointment-only means every visit has the time it deserves. No double-booking, no waiting room overflow.
02 — Convenience

In your neighborhood.

Routine wellness, vaccines, exams, and dental consultations right here in Vermillion — no Yankton drive required.
03 — Continuity

Same team, same records.

Need something more advanced? Surgery, imaging, or urgent care happens at our Yankton clinic — with all your records already in hand.